Vigorus Ingredients: Two Nutrients and a 570 mg Blend

What is in Vigorus capsules?

Each Vigorus capsule holds two nutrients with printed amounts and six ingredients in a 570 mg blend. Four other ingredients form the capsule and help it fill evenly.

All of this comes from the Supplement Facts panel on the bottle. The serving size is 1 capsule, and there are 30 in each bottle.

Niacin and zinc: the two printed amounts

Niacin and zinc are the only ingredients with exact amounts on the label. That makes them the easiest part of Vigorus to judge.

Vitamin B3 comes as niacin, 20 mg per capsule. That is 125% of the Daily Value. Adult men need about 16 mg a day, and most get that from food. The upper limit for niacin from supplements is 35 mg a day. Nicotinic acid can cause skin flushing at 30 mg or more (NIH ODS, niacin).

Zinc comes as zinc oxide, 11 mg per capsule. That equals the daily need for adult men and 100% of the Daily Value. The upper limit is 40 mg a day from food and supplements together (NIH ODS, zinc).

Both amounts sit below their upper limits on their own. The math changes if you also take a multivitamin, which is why how to take Vigorus covers adding them up.

The six blend ingredients in label order

The label lists six ingredients under "Proprietary Blend 570 mg" with no single amount. Here they are from first to last, each with a short research note.

1. L-Citrulline

What it is: amino acid. Listed first, so it is the largest share of the 570 mg blend. It can make up 570 mg of each capsule at the very most.

Research note: Blood pressure studies used about 3 to 10 g a day (Allerton et al., 2018).

2. L-Carnitine

What it is: amino acid compound. A compound the body makes from amino acids; also in meat. It can make up 285 mg of each capsule at the very most.

Research note: Studies used about 1 to 3 g a day; at 3 g or more it can cause stomach upset (NIH ODS, 2023).

3. Pine Bark Extract

What it is: Pinus pinaster, bark. French maritime pine bark; the label does not name a brand or standard. It can make up 190 mg of each capsule at the very most.

Research note: Reviews call the evidence for most uses insufficient; it may add to blood thinners (MSK, 2023).

4. Maca Root Extract

What it is: Lepidium meyenii, root. A root vegetable from the Peruvian Andes. It can make up 143 mg of each capsule at the very most.

Research note: Typical doses run 500 to 3,000 mg a day; rigorous human proof is lacking (LiverTox, 2019).

5. Grape Skin Extract

What it is: Vitis vinifera, skin. The label does not say how much resveratrol or other polyphenols it holds. It can make up 114 mg of each capsule at the very most.

Research note: No standard dose exists for grape skin extract; the label gives no strength. For a plain guide to judging any supplement, see the NIH Office of Dietary Supplements.

6. Saffron Stigmas Extract

What it is: Crocus sativus, stigmas. Listed last, so it is the smallest share of the blend. It can make up 95 mg of each capsule at the very most.

Research note: Five small trials, mostly on mood, used saffron extract daily (Hausenblas et al., 2013).

How much of each blend ingredient could be in a capsule?

Nobody outside the company knows the real amounts. You can still find the most each one could be, because US rules list blend ingredients from most to least by weight.

So the second ingredient can weigh half the blend at most. The third can be a third at most, and so on. Divide 570 mg by the position and you get the ceiling.

No study has tested the Vigorus formula as a whole. The how Vigorus works page explains what that means for the claims on the sales page.

What are the other ingredients?

The other ingredients hold the powder and help the machines fill each capsule. The label lists them as: hypromellose (vegetable capsule), microcrystalline cellulose, magnesium stearate, silicon dioxide.

The shell is hypromellose, a plant-based material, not gelatin. That lines up with the vegetarian seal on the sales page.

What does the label leave out?

The label is clear on totals but quiet on detail. Here is what you cannot learn from the bottle.

• No milligram amount for any of the six blend ingredients
• No standard for pine bark or grape skin, such as a percent of an active compound
• No resveratrol amount for the grape skin extract
• No caffeine or other stimulant
• No manufacturer name, only the distributor in Aurora, CO

Which ingredients are worth a word with your doctor?

A few ingredients touch the same systems as common medicines. If you take any prescription, bring the bottle to your doctor or pharmacist first.

L-citrulline and pine bark touch circulation and may add to blood pressure medicines. Pine bark may also add to blood thinners such as warfarin (MSK, 2023). Zinc can lower how well quinolone and tetracycline antibiotics work, so space them 2 to 6 hours apart. The side effects page covers each one in more depth.

Vigorus ingredients: common questions

Sources for this page

1. Allerton TD, Proctor DN, Stephens JM, Dugas TR, Spielmann G, Irving BA. L-Citrulline supplementation: impact on cardiometabolic health. Nutrients, 2018. Source
2. NIH Office of Dietary Supplements. Carnitine: Fact Sheet for Health Professionals. Updated April 2023. Source
3. Memorial Sloan Kettering Cancer Center. Pine Bark Extract (About Herbs). Updated August 2023. Source
4. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Maca. National Institute of Diabetes and Digestive and Kidney Diseases, 2019. Source
5. Hausenblas HA, Saha D, Dubyak PJ, Anton SD. Saffron (Crocus sativus L.) and major depressive disorder: a meta-analysis of randomized clinical trials. J Integr Med, 2013. Source
6. NIH Office of Dietary Supplements. Niacin: Fact Sheet for Consumers. Updated March 2021. Source
7. NIH Office of Dietary Supplements. Zinc: Fact Sheet for Consumers. Updated October 2022. Source
8. NIH Office of Dietary Supplements. Dietary Supplements: What You Need to Know. Source